By Dr. Paul C. Eck and Dr. Lawrence Wilson
© December
2009, The Center For Development, Inc.
Adrenal
insufficiency refers to the inability of the adrenal glands to produce a normal
quantity of hormones. It may also be defined as a reduced ability to cope with
stress. It is one of the most common imbalances in our population today.
Adrenal
insufficiency is not to be confused with Addison's
disease. Addison's disease is more or less a total adrenal gland
shutdown. Adrenal insufficiency is
also different from adrenal burnout.
The latter is a more severe derangement of the energy-producing mechanisms of
the body. In burnout, the body is basically unable to cope with stress. The
symptoms of burnout are similar to those of adrenal insufficiency, but are more
extreme and require longer to correct.
Click here for a separate article on Adrenal
Burnout.
ABOUT THE ADRENAL GLANDS
The adrenal
glands are often referred to as the stress glands or the fight-or-flight
glands. The fight-or-flight response is mediated by the adrenal medulla. The
fight-or-flight response is the body’s way of responding to stress.
The
stress response prepares the body to run or fight. Blood pressure, pulse rate
and blood sugar levels increase. Blood is shunted away from the digestive
organs and toward the muscles and brain. The pupils dilate and the speed of
reflexes increases. Part of the stress response is due to the action of the
adrenal hormones. Symptoms of adrenal insufficiency can be directly traced to a
reduced secretion of these hormones when under stress. Adrenal hormones are
divided into two groups, those produced in the adrenal medulla and those
produced in the cortex.
Hormones
produced in the medulla are epinephrine and norepinephrine. These are powerful, fast-acting
neurotransmitters which initiate the fight-flight response. They are also
sometimes called adrenalin and noradrenalin. The hormones produced by the
adrenal cortex are aldosterone, cortisol and cortisone. The cortical hormones
have a slower, more prolonged action.
Aldosterone is called a
mineralocorticoid hormone. Its
primary function is to increase sodium retention by the kidneys. Aldosterone levels roughly correlate
with sodium levels on a hair mineral
analysis. Aldosterone is a
pro-inflammatory hormone required to initiate a healing reaction.
Cortisol and cortisone are referred to
as glucocorticoid hormones because they cause conversion of amino acids and
glycogen to glucose. The corticosteroids are anti-inflammatory and provide a
mild sense of euphoria. Cortisol levels roughly correspond to the potassium level on a hair mineral
analysis.
A
balance between aldosterone and cortisol is necessary to maintain one's health.
This balance is very roughly associated with the ratio of sodium to potassium
on a hair analysis. If aldosterone
secretion is high ratio-wise to cortisol, inflammatory conditions such as
gastritis, colitis, arthritis, bursitis and sinusitis prevail. This often corresponds with a high ratio
of sodium to potassium on a hair analysis.
If
cortisol secretion is high ratio-wise to aldosterone, diseases such as
diabetes, immune-deficiency syndromes, infection, arteriosclerosis,
atherosclerosis, cataracts, glaucoma, coronary heart disease or cardiomyopathy
may prevail. This corresponds to a
low ratio of sodium to potassium on a hair analysis. Dr. Eck found the ideal sodium/potassium ratio is about
2.5:1 in an unwashed sample of head hair.
SYMPTOMS OF ADRENAL INSUFFICIENCY
Adrenal
insufficiency is commonly associated with the following symptoms, which can
vary from mild to extreme.
* fatigue
* decreased tolerance to cold
* poor circulation
* low blood sugar level (hypoglycemia)
* low blood pressure
* allergies
* apathy or depression
* low stamina
* low self-esteem due to low energy output
* joint aches and pains
* low levels of gastric hydrochloric acid
* tendency to constipation
* muscle weakness
* need for excessive amounts of sleep
* fears, due to low energy and secondary copper toxicity
* lowered resistance to infection
* subnormal body temperature
CAUSES OF ADRENAL INSUFFICIENCY
Causes of adrenal insufficiency may
include:
· Genetics.
Genetics can affect the adrenal glands. Also, genetic defects can be a cause of
physical and emotional stress that can weaken the adrenals.
· Congenital Weakness. Congenital means present at birth. However, a congential condition may
not be genetic. It may be caused by nutritional deficiencies of the mother that
are passed on to the child. It may also be caused by toxic metals or other
toxins passed on from the mother's body that interfere with the functioning of
the adrenal glands. This is a very common cause of adrenal insufficiency today.
· Nutritional Imbalances. These can begin early in childhood with inadequate diets,
diet inappropriate for one's oxidation type, poor food quality or digestive
problems that prevent proper nutrition. Even natural foods today often are low
in vital minerals and do not provide adequate nutrition. Pesticides, heavy
metals, bacteria, solvents and other organic chemicals can all act as stressors
that weaken the adrenal glands.
· Emotional or Psychological Stress. Responding to emotional stress over and over will
eventually deplete the adrenal glands. A single overwhelming shock such as
death of a loved one can also deplete the adrenals. Emotional stress can begin
in childhood or at any time in life. It is actually the resistance or fear of a
situation that causes the stress response. A loving response will cause much
less of a reaction, no matter what the situation.
Other possible
stressors include pressures from family, school, work, social pressure,
financial stress and others. People who force their bodies to "run or
fight" all the time by any means will tend to exhaust their adrenal
glands. The 'fight-or-flight' response must be balanced by adequate rest and
sleep.
· Stimulants.
Most stimulants whip the adrenals. This may cause one to feel better for a
while, but the long-term effect is to weaken the adrenal glands. Stimulants
include sugar, alcohol, caffeine, theobromine in chocolate, amphetamines and
other medical drugs, cocaine, heroine and others.
Other stimulants
can include loud noise, loud music, light stimulation such as strobe lights in
night clubs, excessive exercise and excessive vibration. Anger, fear and worry
can act as stimulants as well.
Note that
stimulant use can be a result, as
well as a cause of adrenal insufficiency. A person who is tired due to weak
adrenals may be attracted to stimulants such as drugs, loud music or anger to
feel better temporarily.
· Infections, Energetic and Structural Imbalances. These are all internal stressors
that, if left uncorrected, can eventually weaken the adrenals by forcing the
body to mount a chronic stress response to these irritants.
· Toxic Substances. These may include chlorine in water, polluted air, mercury from dental
fillings, household chemicals, food additives, pesticide exposure, dusts, molds
and pollens. These often cause allergies that can be controlled with adrenalin
or cortisone, the adrenal hormones.
Medical therapy,
particularly cortisone or prednisone therapy, weakens the adrenals by creating
hormone imbalances.
· Mental Attitude. One's attitude makes a great difference in determining the stress
response. Worry, fear, anger and resentment tend to increase the stress
response. An attitude of gratitude and compassion for oneself and others tends
to diminish the stress response. Understanding the impermanence of the body and
the world we live in, emotional detachment and detachment from all form, and a
single-minded desire to extend love can greatly diminish the stress response.
DETECTING ADRENAL INSUFFICIENCY
It
is often possible to assess adrenal insufficiency based upon symptoms. Anyone who is tired, allergic,
intolerant to cold, with symptoms of low blood sugar such as craving sweets or
starches, or who is weak, or has low blood pressure most likely has some degree
of adrenal insufficiency.
Blood tests. These are variable and are
often absolutely normal. However,
it is possible that the serum sodium level is less than 130 mEq/L and a serum
potassium greater than 5 mEq/L. A low glucose levels and elevated blood urea
nitrogen (BUN) may also be present. Other factors, however, can affect the
serum readings.
A
blood test for adrenal function involves measuring 17-ketosteroids, a breakdown
product of the adrenal hormones. Measuring the ketosteroids alone is not
considered accurate. To perform the test properly, an injection of ACTH
(adreno-cortical stimulating hormone) is given first. Then urine is collected
and measured for 17-hydroxycorticosteroids (17-OHCS) and 17-ketogenic steroids
(17-KGS).
Measurement
of 17-OHCS and 17-KGS without the ACTH loading is not useful and may be
misleading. The loading dose of ACTH measures how well the adrenals respond to
the pituitary. Many people with adrenal insufficiency have no symptoms if the
adrenals are not called upon to respond to a stressor.
Hair mineral analysis is an excellent
assessment tool for adrenal insufficiency when the test is properly performed.
It is often much more significant, reliable and sensitive than blood or most
other tests provided the test is done correctly and one knows how to interpret
it. The hair must not be washed at
the laboratory. Washing the hair at
the laboratory erratically removes sodium and potassium, critical minerals for
adrenal assessment. According to
the research of Dr. Paul Eck, the following are indicators of adrenal
insufficiency on a hair analysis:
* Sodium level less than
25 mg%
* Potassium level less than 10 mg%
* Sodium/potassium ratio less than 2.5:1
* Sodium/magnesium ratio less than 4.17:1
* Calcium/potassium ratio greater than 10:1
The
more of these indicators that are present, the greater the evidence of adrenal
insufficiency. Also, the more
extreme the values, the more suggestive of adrenal insufficiency problems.
CORRECTING ADRENAL INSUFFICIENCY
The
only medical treatment for adrenal insufficiency is cortisone replacement
therapy. While low dose cortisone
is used by some physicians, this therapy always causes serious side effects. In contrast, nutritional balancing
science will correct most cases of adrenal insufficiency. It involves:
· Nutritional assessment through hair
tissue mineral analysis.
· A wholesome diet of natural foods
appropriate for one's oxidation type and digestive ability.
· Nutritional supplements to reduce
stress and enhance adrenal activity. The adrenal glands especially require
vitamins A, C, E, pantothenic acid, manganese and zinc. Adrenal glandular
substance is also recommended to provide adrenal nucleoproteins and other
specific nutritional factors to help rebuild the adrenal glands.
· Supplements to enhance overall
metabolism, eliminate toxic metals and enhance absorption and digestion of
food.
· Detoxification procedures such as
sauna therapy to help eliminate toxic metals.
· Lifestyle modification to reduce
harmful stressors.
· Techniques to improve one's ability
to cope with stress. This can include biofeedback, meditation, relaxation
techniques, etc.
· Attitude adjustment, including
letting go of resentment, blame, attachments and fears that stimulate but also
can paralyze the adrenal glands.
In
mild cases of adrenal insufficiency, correction can occur in a matter of
months. In more difficult or
longstanding cases, complete correction may require several years. Persistence
and patience are needed for optimal results.
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